Pediatric Neuro-oncology Cell Atlas
Pediatric Neuro-oncology Cell Atlas
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ependymoma; spatial transcriptomics; tumor microenvironment
Spatial transcriptomic analysis delineates epithelial and mesenchymal subpopulations and transition stages in childhood ependymoma
BACKGROUND: The diverse cellular constituents of childhood brain tumor ependymoma, recently revealed by single cell RNA-sequencing, may underly therapeutic resistance. Here we use spatial transcriptomics to further advance our understanding of the …
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