Single-nuclei RNA-seq of childhood PFA Ependymoma recurrence
We examined matched samples of primary and recurrent disease from PFA EPN patients to investigate the biology of recurrence. single-nuclei RNA-seq was performed on 7 matched pairs of primary and 1st relapse tumors.
Data and code availability
snRNA-seq, bulk RNA-seq, and methylation data to be deposited in the National Center for Biotechnology Information Gene Expression Omnibus (GEO) database.
A UCSC cellbrowser, currently private, will be made available for interactive exploration of the data upon publication.
National Institutes of Health (R01 CA237608-01)
Cancer League of Colorado (research grant AWD 173796-SV)
Tanner Seebaum Foundation
Morgan Adams Foundation
University of Colorado’s NIH/NCI Cancer Center (P30CA046934)